1- People who have uncontrolled diabetes

2-Close and open angular glaucoma patients (patients who have eye pressure)

3- People who have iridocyclitis-uveit

4- People who have intense rheumatism

5- People who are born with an absence of iris

6- People who have colored eyes (relatively)

7-People who have unknown systemic disease

8- People who have high expectations

9- People who have especially inflammatory bowel disease or similar systemic disease

10- Patients who are psychoscially instable

11–Patients who use special medication that leave deposition in the eye