1- People who have uncontrolled diabetes
2-Close and open angular glaucoma patients (patients who have eye pressure)
3- People who have iridocyclitis-uveit
4- People who have intense rheumatism
5- People who are born with an absence of iris
6- People who have colored eyes (relatively)
7-People who have unknown systemic disease
8- People who have high expectations
9- People who have especially inflammatory bowel disease or similar systemic disease
10- Patients who are psychoscially instable
11–Patients who use special medication that leave deposition in the eye